FORM 4 o Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). (Print or Type Responses) |
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940 |
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1. | Name and Address of Reporting Person* | 2. | Issuer Name and Ticker or Trading Symbol | 6. | Relationship of Reporting Person(s) to Issuer (Check all applicable) |
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BVF Partners L.P. | Biocryst Pharmaceuticals Inc. ("BCRX") | Director | X 10% Owner | |||||||||||||||||
(Last) | (First) | (Middle) | 3. | I.R.S. Identification Number of Reporting Person, if an entity (Voluntary) | 4. | Statement for Month/Day/Year |
Officer (give title below) |
Other (specify below) |
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227 West Monroe Street, Suite 4800 | December 23, 2002 | |||||||||||||||||||
(Street) | 5. | If Amendment, Date of Original (Month/Day/Year) | 7. | Individual or Joint/Group Filing (Check Applicable Line) Form filed by one Reporting Person X Form filed by More than one Reporting Person |
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Chicago, | Illinois | 60606 | ||||||||||||||||||
(City) | (State) | (Zip) | ||||||||||||||||||
Table I Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned | ||||||||||||||||||||
1. | Title of Security (Instr. 3) |
2. | Transaction Date | 2A. | Deemed Execution Date, if any | 3. | Transaction Code (Instr. 8) |
4. | Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) |
5. | Amount of Securities Beneficially Owned at End of Month (Instr. 3 and 4) | 6. | Ownership Form: Direct (D) or Indirect (I) (Instr. 4) |
7. | Nature of Indirect Beneficial Ownership (Instr. 4) |
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(Month/Day/Year) | (Month/Day/Year) | |||||||||||||||||||||||||||||||||||
Code | V | Amount | (A) or (D) |
Price | ||||||||||||||||||||||||||||||||
Common Stock | 12/23/02 | P | 2,000 | A | $0.89 | (1) | (1)(2) | |||||||||||||||||||||||||||||
Common Stock | 12/23/02 | P | 1,000 | A | $0.89 | (1) | (1)(3) | |||||||||||||||||||||||||||||
Common Stock | 12/23/02 | p | 2,000 | A | $0.89 | (1) | (1)(4) | |||||||||||||||||||||||||||||
2,080,100 | ||||||||||||||||||||||||||||||||||||
*If the form is filed by more than one reporting person, see Instruction 4(b)(v). |
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Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. | ||
POTENTIAL PERSONS WHO ARE TO RESPOND TO THE COLLECTION OF INFORMATION CONTAINED IN THIS FORM ARE NOT REQUIRED TO RESPOND UNLESS THE FORM DISPLAYS A CURRENTLY VALID OMB CONTROL NUMBER. |
FORM 4 (Continued) | Table II Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities) |
1. | Title of Derivative Security (Instr. 3) |
2. | Conversion or Exercise Price of Derivative Security | 3. | Transaction Date (Month/Day/Year) |
3A. | Deemed Execution Date, if any (Month/Day/Year) |
4. | Transaction Code (Instr. 8) |
5. | Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) |
6. | Date Exercisable and Expiration Date (Month/Day/Year) | |||||||||||||||||||
Code | V | (A) | (D) | Date Exercisable |
Expiration Date | |||||||||||||||||||||||||||
7. | Title and Amount of Underlying Securities (Instr. 3 and 4) |
8. | Price of Derivative Security (Instr. 5) |
9. | Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) |
10. | Ownership Form of Derivative Securities: Direct (D) or Indirect (I) (Instr. 4) |
11. | Nature of Indirect Beneficial Ownership (Instr. 4) |
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Title | Amount or Number of Shares | |||||||||||||||||||
Explanation of Responses:
BVF Partners L.P. | ||||||
By: |
BVF Inc., its general partner |
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By: |
/s/ MARK N. LAMPERT ** Signature of Reporting Person |
December 26, 2002 Date |
** |
Intentional misstatements or omissions of facts constitute Federal Criminal Violations. |
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See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). | ||
Note: |
File three copies of this Form, one of which must be manually signed. |
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If space is insufficient, see Instruction 6 for procedure. | ||
Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Control Number. |
FORM 4 (Continued) |
1. |
Biotechnology Value Fund, L.P. |
BIOTECHNOLOGY VALUE FUND, L.P. |
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227 West Monroe Street, Suite 4800 | |||||||||
Chicago, Illinois 60606 | By: | BVF Partners L.P., its general partner | |||||||
By: | BVF Inc., its general partner | ||||||||
By: | /s/ MARK N. LAMPERT **Signature of Reporting Person Authorized Signatory |
December 26, 2002 Date |
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2. | Biotechnology Value Fund II, L.P. | BIOTECHNOLOGY VALUE FUND II, L.P. | |||||||
227 West Monroe Street, Suite 4800 | |||||||||
Chicago, Illinois 60606 | By: | BVF Partners L.P., its general partner | |||||||
By: | BVF Inc., its general partner | ||||||||
By: | /s/ MARK N. LAMPERT **Signature of Reporting Person Authorized Signatory |
December 26, 2002 Date |
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3. | BVF Investments, L.L.C. | BVF INVESTMENTS, L.L.C. | |||||||
227 West Monroe Street, Suite 4800 | |||||||||
Chicago, Illinois 60606 | By: | BVF Partners L.P., its manager | |||||||
By: | BVF Inc., its general partner | ||||||||
By: | /s/ MARK N. LAMPERT **Signature of Reporting Person Authorized Signatory |
December 26, 2002 Date |
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4. | BVF Inc. | BVF INC. | |||||||
One Sansome Street, 31st Floor | |||||||||
San Francisco, California 94104 | By: | /s/ MARK N. LAMPERT **Signature of Reporting Person Authorized Signatory |
December 26, 2002 Date |
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5. | Mark N. Lampert One Sansome Street, 31st Floor San Francisco, California 94104 |
By: | /s/ MARK N. LAMPERT **Signature of Reporting Person Authorized Signatory |
December 26, 2002 Date |
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** |
Intentional misstatements or omissions of facts constitute Federal Criminal Violations. |
|
See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). | ||
Note: |
File three copies of this Form, one of which must be manually signed. |
|
If space is insufficient, see Instruction 6 for procedure. | ||
Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Control Number. |
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SEC 1474 (03-99)