000 - Document - Document And Entity Information link:calculationLink link:definitionLink link:presentationLink 001 - Statement - Consolidated Balance Sheets (Current Period Unaudited) link:calculationLink link:definitionLink link:presentationLink 002 - Statement - Consolidated Balance Sheets (Current Period Unaudited) (Parentheticals) link:calculationLink link:definitionLink link:presentationLink 003 - Statement - Consolidated Statements of Comprehensive Loss (Unaudited) link:calculationLink link:definitionLink link:presentationLink 004 - Statement - Consolidated Statements of Cash Flows (Unaudited) link:calculationLink link:definitionLink link:presentationLink 005 - Disclosure - Note 1 - Significant Accounting Policies link:calculationLink link:definitionLink link:presentationLink 006 - Disclosure - Note 2 - Stock-based Compensation link:calculationLink link:definitionLink link:presentationLink 007 - Disclosure - Note 3 - Collaborative and Other Research and Development Contracts link:calculationLink link:definitionLink link:presentationLink 008 - Disclosure - Note 4 - Royalty Monetization link:calculationLink link:definitionLink link:presentationLink 009 - Disclosure - Note 5 - Senior Credit Facility link:calculationLink link:definitionLink link:presentationLink 010 - Disclosure - Note 6 - Stockholders' Equity link:calculationLink link:definitionLink link:presentationLink 011 - Disclosure - Significant Accounting Policies (Policies) link:calculationLink link:definitionLink link:presentationLink 012 - Disclosure - Note 1 - Significant Accounting Policies (Tables) link:calculationLink link:definitionLink link:presentationLink 013 - Disclosure - Note 2 - Stock-based Compensation (Tables) link:calculationLink link:definitionLink link:presentationLink 014 - Disclosure - Note 5 - Senior Credit Facility (Tables) link:calculationLink link:definitionLink link:presentationLink 015 - Disclosure - Note 1 - Significant Accounting Policies (Details Textual) link:calculationLink link:definitionLink link:presentationLink 016 - Disclosure - Note 1 - Significant Accounting Policies - Fair Value of the Company's Investments by Type (Details) link:calculationLink link:definitionLink link:presentationLink 017 - Disclosure - Note 1 - Significant Accounting Policies - Scheduled Maturity for the Company's Investments (Details) link:calculationLink link:definitionLink link:presentationLink 018 - Disclosure - Note 1 - Significant Accounting Policies- Summary of Receivables (Details) link:calculationLink link:definitionLink link:presentationLink 019 - Disclosure - Note 1 - Significant Accounting Policies - Cumulative Effective Adopted Accounting Pronouncement (Details) link:calculationLink link:definitionLink link:presentationLink 020 - Disclosure - Note 1 - Significant Accounting Policies - Summary of Revenues (Details) link:calculationLink link:definitionLink link:presentationLink 021 - Disclosure - Note 2 - Stock-based Compensation (Details Textual) link:calculationLink link:definitionLink link:presentationLink 022 - Disclosure - Note 2 - Stock-based Compensation - Stock Incentive Plan Activities (Details) link:calculationLink link:definitionLink link:presentationLink 023 - Disclosure - Note 2 - Stock-based Compensation - Weighted Average Assumptions for Stock Option Awards Granted to Employees and Directors Under the Incentive Plan (Details) link:calculationLink link:definitionLink link:presentationLink 024 - Disclosure - Note 3 - Collaborative and Other Research and Development Contracts (Details Textual) link:calculationLink link:definitionLink link:presentationLink 025 - Disclosure - Note 4 - Royalty Monetization (Details Textual) link:calculationLink link:definitionLink link:presentationLink 026 - Disclosure - Note 5 - Senior Credit Facility (Details Textual) link:calculationLink link:definitionLink link:presentationLink 027 - Disclosure - Note 5 - Senior Credit Facility - Scheduled Principal Repayments of the Credit Facility (Details) link:calculationLink link:definitionLink link:presentationLink 028 - Disclosure - Note 6 - Stockholders' Equity (Details Textual) link:calculationLink link:definitionLink link:presentationLink