BIOCRYST TO RELEASE FIRST QUARTER FINANCIAL RESULTS ON APRIL 23, 2003

April 10, 2003
BIOCRYST TO RELEASE FIRST QUARTER FINANCIAL RESULTS ON APRIL 23, 2003 Birmingham, Alabama – April 10, 2003 – BioCryst Pharmaceuticals, Inc. (Nasdaq NM: BCRX) will release its financial results for the first quarter 2003, before the market opens on Wednesday, April 23, 2003. The Company will also sponsor a conference call at 10:00 a.m. EDT. Interested investors can listen to the call live over the Internet from the investor relations website at www.biocryst.com or by dialing 1-800-946-0709, and providing the passcode number 614113.

What:
BioCryst Pharmaceuticals, Inc. First Quarter 2003 Financial Results Conference Call

When:
Wednesday, April 23, 2003, 10:00 a.m., EDT

Where:
http://www.firstcallevents.com/service/ajwz378824453gf12.html

How:
Live over the Internet -- Simply log on to the web at the address above, or
Live conference call -- Dial 1-800-946-0709, passcode 614113.

Founded in 1986, BioCryst Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development of small-molecule pharmaceuticals to prevent, treat, and control cancer, cardiovascular diseases and viral infections.

For those unable to listen at the designated time, the webcast will remain available for replay over BioCryst's investor relations website until May 23, 2003. A conference call replay will also be available from approximately 1:00 p.m. EDT on Wednesday, April 23, 2003 through midnight Friday, April 25, 2003 by dialing 1-888-203-1112 and entering passcode 614113.