Press Release Details

Birmingham, Alabama - December 9, 2003 - BioCryst Pharmaceuticals, Inc. (Nasdaq NM: BCRX) announced that Charles E. Bugg, Ph.D., Chairman and CEO, will be presenting at the Harris Nesbitt Gerard Focus on Healthcare conference in New York on Thursday, December 11, 2003, at 9:00 a.m. Eastern Standard Time. Interested investors can listen to the presentation live over the Internet during the conference at the following address:

http://www.corporate-ir.net/ireye/confLobby.zhtml?ticker=BCRX&item_id=802409

What:
BioCryst Pharmaceuticals, Inc. Presentation at the Harris Nesbitt Gerard Healthcare Conference

When:
Thursday, December 11, 2003, at 9:00 a.m. EST

Where:
http://www.corporate-ir.net/ireye/confLobby.zhtml?ticker=BCRX&item_id=802409

How:
Live over the Internet -- Simply log on to the web at the address above

For those unable to listen at the designated time, the webcast will remain available for replay on http://www.corporate-ir.net/ireye/confLobby.zhtml?ticker=BCRX&item_id=802409 for 90 days following the conference.

Founded in 1986, BioCryst Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development of small-molecule pharmaceuticals to treat cancer, cardiovascular and autoimmune diseases, and viral infections.