BIOCRYST TO RELEASE THIRD QUARTER FINANCIAL RESULTS

October 10, 2003
BIOCRYST TO RELEASE THIRD QUARTER FINANCIAL RESULTSBirmingham, Alabama - October 10, 2003 - BioCryst Pharmaceuticals, Inc. (Nasdaq NM: BCRX) will release its financial results for the third quarter 2003, before the market opens on Monday, October 20, 2003. The Company will also sponsor a conference call at 10:00 a.m. EDT. Interested investors can listen to the call live over the Internet from the investor relations website at www.biocryst.com or by dialing 1-800-406-5356, and providing the passcode number 601959.

What:
BioCryst Pharmaceuticals, Inc.
Third Quarter 2003 Financial Results Conference Call

When:
Monday, October 20, 2003, 10:00 a.m., EDT

Where:
http://www.firstcallevents.com/service/ajwz390190556gf12.html

How:
To listen live over the Internet simply log on to the web address above. To access the live audio conference call, simply dial:

1-800-406-5356, Passcode 601959

For those unable to listen at the designated time, the webcast will remain available for replay over BioCryst's investor relations website until November 20, 2003. A conference call replay will also be available from approximately 1:00 p.m. EDT on Monday, October 20, 2003 through midnight Wednesday, October 22, 2003 by dialing 1-888-203-1112 and entering passcode 601959.

Founded in 1986, BioCryst Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development of small-molecule pharmaceuticals to treat cancer, cardiovascular and autoimmune diseases and viral infections.

Contacts:

BioCryst Pharmaceuticals, Inc.
Mike Darwin
Chief Financial Officer
(205) 444-4600

Euro RSCG Life NRP
Sharon Weinstein (Investors)
(212) 845-4271
Wendy Lau (Media)
(212) 845-4272