BIOCRYST TO RELEASE FIRST QUARTER 2004 FINANCIAL RESULTS

April 15, 2004
BIOCRYST TO RELEASE FIRST QUARTER 2004 FINANCIAL RESULTSBirmingham, Alabama - April 15, 2004 - BioCryst Pharmaceuticals, Inc. (Nasdaq NM: BCRX) will release its financial results for the first quarter 2004, before the market opens on Wednesday, April 21, 2004. The Company will also sponsor a conference call at 10:00 a.m. EST. Interested investors can listen to the call live over the Internet from the investor relations website at www.biocryst.com or by dialing 1-800-395-0708, and providing the passcode number 145089.

What:
BioCryst Pharmaceuticals, Inc. First Quarter 2004 Financial Results Conference Call

When:
Wednesday, April 21, 2004, 10:00 a.m., EST

Where:
http://www.firstcallevents.com/service/ajwz404445462gf12.html

How:
Live over the Internet -- Simply log on to the web at the address above, or Live conference call -- Dial 1-800-395-0708, passcode 145089.

Founded in 1986, BioCryst Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development of small-molecule pharmaceuticals to treat cancer, cardiovascular and autoimmune diseases and viral infections.

For those unable to listen at the designated time, the webcast will remain available for replay over BioCryst's investor relations website until May 21, 2004. A conference call replay will also be available from approximately 1:00 p.m. EST on Wednesday, April 21, 2004 through midnight Friday, April 23, 2004 by dialing 1-888-203-1112 and entering passcode 145089.