BIOCRYST TO RELEASE THIRD QUARTER 2004 FINANCIAL RESULTS

October 12, 2004
BIOCRYST TO RELEASE THIRD QUARTER 2004 FINANCIAL RESULTS

Birmingham, Alabama - October 13, 2004 - BioCryst Pharmaceuticals, Inc. (Nasdaq NM: BCRX) will release its financial results for the third quarter 2004, before the market opens on Wednesday, October 20, 2004. The Company will also sponsor a conference call at 10:00 a.m. ET. Interested investors can listen to the call live over the Internet from the investor relations website at www.biocryst.com or by dialing 1-800-289-0498, and providing the passcode number 846404.

What:

BioCryst Pharmaceuticals, Inc. Third Quarter 2004 Financial Results Conference Call

When:

Wednesday, October 20, 2004, 10:00 a.m., ET

Where:

http://phx.corporate-ir.net/playerlink.zhtml?c=74878&s=wm&e=950987

How:

Live over the Internet -- Simply log on to the web at the address above, or Live conference call -- Dial 1-800-289-0498, passcode 846404.

Founded in 1986, BioCryst Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development of small-molecule pharmaceuticals to treat cancer, cardiovascular diseases, autoimmune diseases and viral infections.

For those unable to listen at the designated time, the webcast will remain available for replay over BioCryst's investor relations website until November 20, 2004. A conference call replay will also be available from approximately 1:00 p.m. ET on Wednesday, October 20, 2004 through midnight Friday, October 22, 2004 by dialing 1-888-203-1112 and entering passcode 846404.

Contacts: BioCryst Pharmaceuticals, Inc.
Michael A. Darwin
Chief Financial Officer
(205) 444-4600

Euro RSCG Life NRP
Sharon Weinstein (Investors)
(212) 845-4271
Wendy Lau (Media)
(212) 845-4272